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Tocotrienols: The Best Vitamin E For Your Health

Tocotrienols: The Best Vitamin E For Your Health

Most people have heard that Vitamin E is excellent for health. However, it appears that you have been misinformed by the potency and effectiveness of the Vitamin E sold in stores.

Let me introduce you to tocotrienols, the component in Vitamin E that is the real knight in shining armor for your health.

Do you want to protect your heart, cholesterol levels, lungs, bone health, liver, and much more? Then please read this article until the end to discover how beneficial “tocotrienol Vitamin E” is.

Here you will find the best food source of tocotrienols, where to buy the supplement, and more.

What Exactly Are Tocotrienols?

Vitamin E consists of two compounds, with each having four sub-components. They are:

  1. Tocopherols – which include alpha, beta, gamma, and delta
  2. Tocotrienols – which include alpha, beta, gamma, and delta

The Vitamin E you purchase in stores does not have enough tocotrienol content or if any at all, nor is it good quality for your health, and it primarily contains alpha-Tocopherol.

Tocotrienols: The Best Vitamin E For Your Health
Two Sample Labels Found On Commercially Sold Vitamin E (No Tocotrienols)

Even the food you eat contains Vitamin E in the form of alpha-Tocopherol. Only a handful of food sources have tocotrienols, which will be discussed later in the article.

Of the four tocotrienols, delta-tocotrienol has the most significant antioxidant potency. 

Note: The word “tocopherols” in this article refers to alpha-Tocopherol because it is the most consumed worldwide.

What Is The Difference Between Tocopherols And Tocotrienols? 

For starters, alpha-Tocopherol has gotten all the attention from scientists in the last century as being “the most biologically active and potent antioxidant currently in existence,” according to this 2021 study.

However, the study then follows by saying that many research reports confirm that tocotrienols are more potent and beneficial to health and have proven so as being or having better :

  • antioxidant
  • anti-inflammatory 
  • anti-cholesterolaemic (cholesterol-lowering)
  • anti-cancer 
  • anti-diabetic 
  • anti-atherogenic (protects arteries
  • blood pressure-lowering
  • neuroprotective effects (protects the nervous system and its cells)

Unfortunately, to date, many scientists are overlooking the potential health benefits of tocotrienols because of their scarcity in foods.

There is only one particular food source where you can get the purest tocotrienols. More on this later.

Tocotrienols Are A Much More Potent Antioxidant 

Studies have identified that tocotrienols have a much more antioxidant effect than alpha-tocopherol. In other words, they are better at searching for and destroying free radicals that cause damage to your body. (See Section 5 of this 2021 study)

In addition, there is evidence that alpha-Tocopherol, the most used form of Vitamin E, is second-rate and at times harmful to the body.

Studies have shown that if alpha-Tocopherol is taken on its own, it may cause:

  • premature breakdown of prescription drugs 
  • an increase in cholesterol and blood pressure 
  • an increased chance of getting prostate cancer 

Tocotrienols Are More Beneficial And Effective

Barrie Tan, Ph.D., the foremost expert and discoverer of tocotrienols, and has studied them for over 35 years, stated the following:

  • Tocotrienols protect each one of our 37 trillion cells from oxidation…Over 90% of oxidation protection must come from either tocotrienols or tocopherols. Tocotrienols are the better choice as they have been shown to provide 40-60 times more protection than tocopherols, especially delta-tocotrienols.

As you can see, tocotrienols compared to tocopherols is like comparing a lion to a kitten. 

And Tan, who is well-respected in the medical community, further stated that alpha-Tocopherol is Vitamin E’s weakest component. But yet, this is what is presently sold to the mass worldwide.

On the other hand, tocotrienols are more effective because of their smaller size, speed, and agility; they can travel throughout your body much faster than tocopherols. In essence, they reach your organs quicker which results in faster health protection.

Many studies have confirmed that alpha-Tocopherol is not effective at preventing and treating chronic diseases. On the flip side, scientific interest is starting to get intense for tocotrienols “due to their special health benefits.”

Countless studies are showing the superiority of tocotrienols for your health. (See Table 5 here) These discoveries are making scientists investigate if tocotrienols are the Vitamin E of the future.

What Is The Best Natural Source Of Tocotrienols?

Tocotrienols are incredibly scarce in foods. They are found in small quantities in everyday foods like oats, olive oil, rye, flaxseed oil, and sunflower oil.

But the three primary sources of tocotrienols are:

  1. Rice bran oil
  2. Palm oil
  3. Annatto

Out of these three, Annatto is the only food source globally that contains 100% tocotrienols with zero tocopherol content, making it the best source to get the purest tocotrienol content. 

Rice bran oil is made up of 50% tocopherols and 50% tocotrienols. In comparison, palm oil consists of 25% tocopherols and 75% tocotrienols.

Why Is Annatto the Best Source Of Tocotrienols?

Tocotrienols: The Best Vitamin E For Your Health

Annatto is a plant that was first discovered in the Amazon Rainforest in the 16th century. The plant has been used for medicinal purposes for millennia.

Many studies have shown that alpha-Tocopherol interferes with tocotrienols’ absorption and delivery process to different organs in your body, rendering them ineffective and unable to fight diseases.

Tocotrienols will work best when the Vitamin E you ingest has a ratio of 90% tocotrienols or more and 10% tocopherols or less. The only natural source that meets these criteria is Annatto, containing 100% tocotrienols and zero tocopherols.

Annatto Supplements

For most people, it will be challenging to obtain the Annatto plant. No worries, you can easily purchase the supplement on Amazon worldwide. Just go to Amazon and search for Annatto.

Remember, try to find a supplement that does not contain more than 10% of tocopherols to reap the health benefits of Annatto Vitamin E.

A 100% Annatto supplement would be best. Here is a perfect example found on Amazon US.

What Are The Health Benefits Of Tocotrienols?

As stated earlier in the article, tocotrienols protect every cell in your body. Theoretically, they should protect you from all diseases and ailments. However, let us look at what studies have discovered.

The following is based on research conducted by the scientist who discovered tocotrienols, Dr. Barrie Tan. But it will be supported with other independent studies.

Helps With Inflammation

Scientists have theorized that chronic inflammation is the root of many diseases known today.

In other words, if you can find something that can control inflammation, you can treat or prevent most diseases and ailments.

research report published in 2021 investigated many human studies that were conducted with tocotrienols for inflammation.

The results of the studies were evident. Tocotrienols significantly controlled inflammation by reducing C-reactive protein (CRP) levels.

C-reactive protein is an inflammatory protein made most by the liver. Whenever you have an infection or inflammation somewhere in your body, its level increases up to 1000 times in the infected area.

Tocotrienols, especially the delta variety found in abundance in Annatto, have been proven(1), (2) that they can significantly reduce inflammation by lowering CPR levels.

For Bone Health

Numerous studies (3), (4), (5), (6) suggest that tocotrienols vastly improve bone health.

The studies all mention Annatto as being the most beneficial for your bones.

Another research report that reviewed numerous studies on tocotrienols for bone health concluded that they reduce bone loss and improve bone health.

Dr. Ima-Nirwana Soelaiman, MBBS, PhD., has studied tocotrienols since 1994. Her research confirms that tocotrienols,

  • “…increase bone’s microstructural integrity. They increase bone calcium content and bone mechanical strength. They inhibit bone resorption and increase bone formation.” 

Not only can tocotrienols prevent bone loss, but they can also treat and reverse the process if you already have osteoporosis.

Beneficial For Nonalcoholic Fatty Liver Disease

Most people think that only people that drink heavily suffer from fatty liver disease or cirrhosis of the liver.

However, this is far from the truth. It appears that people who never drink alcohol suffer from fatty liver disease. It is called “Nonalcoholic Fatty Liver Disease.” (NAFLD)

NAFLD is the result of the unhealthy Western diet. According to D. Tan, NAFLD is going to be an epidemic in this century.

In a study conducted on 71 people who had NAFLD, they were given tocotrienols from Annatto for 12 weeks. The results showed that tocotrienols were effective at reducing the fat in their livers.

Other Health Benefits Discovered In Human Studies

Numerous studies have been conducted on humans using tocotrienols. The following benefits were discovered:

  • They can Protect Your Cardiovascular system 
  • They fight breast and pancreatic cancer
  • They protect your skin
  • Tocotrienols are beneficial for the nervous system and brain
  • They help regulate your immune system 
  • They reduce DNA damage in people over 50
  • They fight aging

There are a host of many health benefits that tocotrienols can prevent and treat.

Tocotrienols: The Best Vitamin E For Your Health
 Creative Commons Attribution License Unrestricted Use Photo


Studies have suggested that 200-1000 milligrams daily is a safe dosage.

Dr. Tan stated that the average person with no health issues should take between 100-200 mg of Annatto supplement per day, while a person with a health problem should take 300-600 mg per day.

Tocotrienol supplements should be taken with food and should especially include some fatty foods. The fat enhances the bioavailability of tocotrienols


Remember, if you eat foods containing alpha-tocopherol Vitamin E while taking tocotrienol supplements, they will interfere with tocotrienols’ workings and render them ineffective.

Side Effects

As for tocotrienol side effects, there are none at present. Both short and long-term human studies showed that they are safe to take by anyone, including pregnant women.

Do not take more than the dosage recommended by the experts unless under the guidance of your medical provider.


There is well-defined evidence that tocotrienols have many more health benefits than alpha-Tocopherol Vitamin E.

Annato is the best natural source for tocotrienols, and you can easily find its supplement on Amazon.

Forget the Vitamin E sold in stores; they do nothing for your health compared to tocotrienol Vitamin E. 

Tocotrienols are the mysterious Vitamin E that not many people are aware of. Scientists are beginning to see the wonders they can create for your health. Some day this will be the foremost Vitamin E sold commercially throughout the world.

Want to protect every cell in your body? Then you must add tocotrienols to your supplements list.