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What Is The Best Black Seed Oil To Take?

What Is The Best Black Seed Oil To Take?

The claims of black seed oil (BSO) as a treatment or preventative for many diseases or ailments are becoming well-known worldwide.

And there is plenty of scientific evidence to support the above assertion.

As Prophet Muhammad said, “The black seed can heal every disease, except death.

The bottom line is that black seed oil can help with many diseases, viruses, bacteria, etc.

But, what is the best black seed oil to use? Not all BSO is the same or as beneficial for health.

Also, most people are not aware that black seed oil shows a low oral bioavailability and has poor health benefits when taken orally. (Bioavailability means being better able to enter your circulation to have a more substantial medicinal effect)

This article will provide you with scientific evidence on the best black seed oil to take and why.

Many people assume that the oil itself is medicinal. However, this is not so. Black seed oil contains numerous potent constituents, but a particular one called thymoquinone (TQ) is mostly responsible for its full medicinal benefits. 

In other words, it’s not the amount of BSO you ingest; it’s the quality and quantity of thymoquinone in the BSO that matters. 

The best black seed oil to look for is one with a high-quality TQ content.

What Are The Benefits Of Thymoquinone?

What Is The Best Black Seed Oil To Take?

Nigella Sativa (NS) is the plant that the oil is extracted from. 

It is one of the most treasured nutrient-rich herbs in the history of the world.

The NS oil’s effectiveness is mostly linked to TQ, the primary active compound making up 30–48% of all the NS compounds. 

There are other numerous beneficial components in NS, which include, but not limited to:

  • p-cymene
  • carvacrol
  • thymohydroquinone  
  • dihydro-thymoquinone 
  • α-thujene
  • thymol 
  • t-anethole
  • β-pinene
  • α-pinene 
  • γ-terpinene
  • nigellidine

But to reiterate, TQ is the most studied by scientists because it mostly makes black seed oil medicinally useful.

Yes, NS is exceptionally nutritious and is filled with over 100 beneficial compounds. However, IT IS THYMOQUINONE THAT GIVES IT ITS POTENT THERAPEUTIC BENEFITS.

TQ’s primary medicinal uses include but are not limited to: Sources, (1), (2), (3), (4), (5), (6)

  • anticonvulsant (can control or prevent, or stop an ongoing series of seizures)
  • antimicrobial
  • anticancer
  • antihistaminic
  • antidiabetic
  • anti-inflammatory 
  • antioxidant
  • gastroprotective
  • neuroprotective (protects the brain)
  • anti-arthritic
  • hepatoprotective (protects the liver)
  • treats and prevents respiratory diseases
  • nephroprotective (protects the kidneys)
  • protects the reproductive system
  • cardio-protective
  • hypoglycemic
  • immune stimulation 
  • auto-immune disorders
  • metabolic syndrome (a group of risk factors that raises your risk for heart disease and other health problems, such as diabetes and stroke)
  • mental illness

As can be seen, TQ is what makes black seed oil so unique and potent.

How Much Thymoquinone Is In Black Seed Oil?

The problem with determining the exact amount of thymoquinone in commercially sold black seed oil is problematic because it is not regulated by law that companies add this to their label.

However, we can get a general idea of BSOs’ thymoquinone content with known studies conducted on different types of BSO brands.

Generally, most of BSO’s thymoquinone content sold on the market is less than 2%.

A 2016 study was conducted to determine how much TQ is in BSO. Researchers used two different methods of extracting the oil from the N. Sativa seeds. The results were as follows: 

Supercritical Fluid Extraction (SFE) Method

  • 6.63 mg of thymoquinone per each milliliter (mL) of oil was found

Cold-Pressed (CP) Extraction Method

  •  1.56 mg of thymoquinone per each milliliter of oil was found

What this means is:

1 Teaspoon = 4.93 mL (Source)

  • SFE – 6.63 mg X 4.93 = 32.68 mg of TQ in one teaspoon of Supercritical Fluid BSO
  • CP – 1.56 mg X 4.93 mL = 7.69 mg of TQ in one teaspoon of Cold-Pressed BSO

The results show that Supercritical Fluid black seed oil has a more considerable amount of TQ, making it more potent to fight disease.

And the study concluded that,

  • The SFE method can be considered as the optimum process for the extraction of NSO since the method enhances the quality of the yield in comparison with CP.

The study further concluded that the SFE oil showed higher antioxidant potency than the CP oil.

An earlier 2010 study also confirms that SFE technology is able to extract higher levels of thymoquinone.

Yet another research report stated the following about SFE black seed oil:

  • It has many advantages compared to conventional extraction methods. 
  • It does not leave any trace of organic solvents.  
  • It has low toxicity
  • Good safety
  • Cheap
  • Abundant in pure form (food grade)
  • Low critical temperature and pressure 

What Exactly is SFE?

According to an August 2020 study, supercritical fluid extraction (SFE) is,

  • “...one of the best techniques for removing natural chemical components such as flavonoids, essential oils, seed oils, carotenoids, and fatty acids from natural plant materials, and it represents a sustainable alternative to traditional extraction systems.” 

SFE technology also ensures a safe and high-quality extract, thus making it more potent, more beneficial, and more bioavailable when ingested.

So, Which May Be The Best Black Seed Oil On The Market?

SFE Black Seed Oil Recommendation

Studies have shown that SFE black seed oil is much more potent and contains a more considerable amount of high-grade and high-quality thymoquinone. 

If you are interested in purchasing SFE oil, you can buy it from Zatik Naturals.

This particular brand is so good that ABC 7 News even spoke about it in one of its segments.

Zatik black seed oil was also praised on Buzzfeed, a world-renowned website for news and all kinds of information. 

Science confirms that SFE oil is the best black seed oil that produces the most health benefits.

Cold-Pressed Back Seed Oil Recommendation

If you are interested in the cold-pressed variety, I recommend ThymoQuin

ThymoQuin contains 3% thymoquinone, and it is in its purest form. And it produces 2-3 times the thymoquinone content of other varieties.

Scientific Evidence Shows That ThymoQuin Is Effective Against Diseases

According to the company’s research, this black seed oil is exceptional because:

  • It is the first cold-press oil standardized to 3% Thymoquinone 
  • It enhances the anti-inflammatory effect of omega-3 fatty acids 
  • 0.45 grams ThymoQuin 3% has the same anti-inflammatory activity as 1 gram pure Curcumin C3
  • It demonstrates superior benefits to other N. Sativa products on oxygen consumption, blood pressure, and blood glucose mechanisms
  • Significant clinical support for anti-inflammatory, cardiovascular, upper respiratory, and blood-sugar benefits

If you wish to purchase ThymoQuin Black Seed Oil, you can buy it HERE.

Please Read Their Review First

As stated earlier in the article, studies show that most black seed oils sold commercially have low oral bioavailability, making them ineffective against diseases. 

For the above reasons, I believe that ThymoQuin may be an excellent source of black seed oil in the cold-pressed family.

ThymoQuin also claims the following synergistic ratio that works together with its 3% thymoquinone content:

Free Fatty Acids

  • ThymoQuin has VERY low levels of free fatty acids making it better for inflammation. High levels do not fight inflammation as well.


  • Studies show that black seed oil works best against inflammation is when the P-Cymene ratio is at 1% to Thymoquinone at 3%. ThymoQuin has this ratio.


  • ThymoQuin has very low levels of carvacrol. At high levels, this compound reduces blackseed oil’s medicinal benefits.


Most black seed oils sold on the market are ineffective against diseases due to their low thymoquinone content or low oral bioavailability.

Supercritical Fluid Extraction (SFE) black seed oil has been scientifically proven to be of a higher standard and higher quality, making it more beneficial and bioavailable.

Thymoquin BSO and the process used to extract it from the seeds make it potent and effective.

Zatik sells a premium ThymoQuin black seed oil that is checked by third parties to ensure that all heavy metals are removed from it.

Heavy metals in black seed oil make it dangerous for people with weakened immunity.

This is a reason why many people get side effects, such as headaches, nausea, stomach aches, itching, etc., when taking black seed oil.

BSO works wonders. However, the right one must be ingested – particularly with the best quality thymoquinone and the most bioavailable.